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Commonly referred to as “poor circulation,” Peripheral Arterial Disease (P.A.D.) is the restriction of blood flow in the arteries of the leg. When arteries become narrowed by plaque (the accumulation of cholesterol and other materials on the walls of the arteries), the oxygen-rich blood flowing through the arteries cannot reach the legs and feet.
The presence of P.A.D. may be an indication of more widespread arterial disease in the body that can affect the brain, causing stroke, or the heart, causing a heart attack.
Over time, the high blood sugar levels associated with diabetes can damage the nerves. This type of nerve damage is known as diabetic polyneuropathy.
If the peripheral nerves become damaged it can cause the following symptoms:
Over time, diabetic polyneuropathy can cause a diabetic foot ulcer (an open sore that develops in the foot). If the ulcer becomes infected, there is a risk that the foot tissue will begin to die and it may be necessary to amputate the foot.
Source: NHS choices